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Real-time monitoring and control for high-efficiency autonomous laser fabrication of silicon nanoparticle colloids

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Abstract

Nanotechnology is a significant research tool for biological and medical research with major advancements achieved from nanoparticle (Np) applications in biosensing and biotherapeutics. For laser ablation synthesis in solution (LASiS) to be chosen by researchers for Np colloid production, the process must effectively compete with chemical synthesis in terms of produced colloid quality and productivity while taking advantage of LASiS benefits in terms of its ‘green-synthesis’ and single-step functionalisation abilities. In this work, a newly developed integrated LASiS Np manufacturing system is presented including a Np flow reactor design, an at-line Np size monitoring via 180° dynamic light scattering, and a UV-Vis spectroscopy system used to estimate colloid concentration and stability. The experimental outcomes are discussed in terms of Np productivity and quality via these at-line measurements from the UV-Vis and DLS systems. The developed instrument was validated via off-line SiNps DLS, UV-Vis and morphology tests via TEM. Ultra-high quality and nanoparticle fabrication rate efficiency was achieved and is reported here.

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Data files are available online: https://doi.org/10.17632/m48784x79n.1.

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Funding

This publication has emanated from research supported the School of Biotechnology, Dublin City University and by research grants from Science Foundation Ireland (SFI) under Grant Number 12/IA/1576 and Grant 16/RC/3872 and is co-funded under the European Regional Development Fund and by I-Form industry partners, and from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 862000.

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Authors and Affiliations

  1. I-Form Advanced Manufacturing Research Centre, Dublin City University, Glasnevin, Dublin 9, Ireland

    Brian Freeland, Ronan McCann, Paul O’Neill, Sithara Sreenilayam & Dermot Brabazon

  2. Advanced Processing Technology Research Centre, School of Mechanical and Manufacturing Engineering, Dublin City University, Glasnevin, Dublin 9, Ireland

    Brian Freeland, Ronan McCann, Paul O’Neill, Sithara Sreenilayam, Greg Foley & Dermot Brabazon

  3. School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland

    Brian Freeland & Greg Foley

  4. National Centre for Plasma Science and Technology, Glasnevin, Dublin 9, Ireland

    Ronan McCann, Paul O’Neill & Dermot Brabazon

  5. Lucerne University of Applied Sciences and Arts, CH-6002, Luzern, Switzerland

    Manuel Tiefenthaler

  6. School of Engineering and Architecture, HES-SO University of Applied Sciences and Arts Western Switzerland, Bd de Pérolles 80, CH-1700, Fribourg, Switzerland

    Michal Dabros & Mandy Juillerat

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  1. Brian Freeland
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Correspondence to Ronan McCann.

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Freeland, B., McCann, R., O’Neill, P. et al. Real-time monitoring and control for high-efficiency autonomous laser fabrication of silicon nanoparticle colloids. Int J Adv Manuf Technol 114, 291–304 (2021). https://doi.org/10.1007/s00170-021-06772-6

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